Benzocaine

• CAS: 94-09-7
• Catalog Number: ALC-FP-94097
• Category: Featured Products
• Molecular Weight: 165.19 g/mol
• Molecular Formula: C9H11NO2
• Appearance: White solid
• Ignition Residue: 0
• Nuclear Magnetic Resonance: Conforms to structure
• Sample Lot No.: A24Q48061HR8
• Water Content: 0.16% (KF)

Case Study

Benzocaine for the Fabrication of High-Performance Al-Mg-Cu LTH Supercapacitor Electrodes

Mohammadi S, et al. International Journal of Hydrogen Energy, 2026, 199, 152799.

Benzocaine was grafted onto Al-Mg-Cu layered triple hydroxide (LTH) via a hydrothermal process to develop high-performance supercapacitor electrodes. Al-Mg-Cu LTH was synthesized through urea-assisted co-precipitation of Cu(NO3)2, Al(NO3)3, and Mg(NO3)2 at 100 °C for 12 h, followed by static aging and refluxing at 94 °C. For hybridization, benzocaine and LTH dispersions were combined in an autoclave and heated at 130 °C for 20 h. The resulting composite was loaded directly onto nickel foam without binders. This binder-free electrode demonstrated facile fabrication, uniform material deposition, and potential for enhanced electrochemical performance, illustrating a practical application of benzocaine in energy storage materials.

Benzocaine for Topical Anesthetic Delivery via Mesoporous Silica-Polysaccharide Hydrogels

Elmotasem H, et al. Results in Chemistry, 2023, 5, 100830.

Benzocaine was encapsulated in mesoporous silica nanoparticles (MSNs) and incorporated into polysaccharide-based hydrogels for sustained topical anesthesia. MSNs were dispersed in aqueous benzocaine solution, sonicated, and stirred for 24 h to achieve high drug-entrapment efficiency, then collected by centrifugation. Hydrogels were prepared by grafting polyacrylic acid onto pullulan, dextran, acacia, or amino cellulose. Cotton gauze was treated in situ using a cold-pad-batch method, immersing it in the hydrogel-MSN-benzocaine solution and squeezing with 100 % wet pick-up, achieving a final benzocaine loading of 0.25 mg/cm². This method provides controlled drug release and practical application in wound dressings or local anesthesia.