allium cepa bulb extract

• CAS: 8054-39-5
• Catalog Number: ACM8054395
• Category: Main Products

Case Study

Comparison of Bioactive Potential: Onion Peel vs. Bulb Extracts

Masood, S., et al. Brazilian Journal of Biology 83 (2021): 00264.

Objective: Assess the antioxidant potential and enzyme inhibitory activity of Allium cepa bulb extracts compared to onion peel extracts.
Key Findings:
· Ethanolic bulb extract contained significantly lower Total Phenolic Content (TPC) and Total Flavonoid Content (TFC) than ethanolic peel extract.
· Across multiple assays (DPPH, FRAP, ABTS, H2O2 scavenging, Fe2+ chelation), the ethanolic bulb extract demonstrated weaker antioxidant and free-radical scavenging activity compared to peel extract. The aqueous bulb extract exhibited the weakest antioxidative potential overall.
· Enzyme Inhibition Implication: The study correlated higher phenolic/flavonoid content with greater α-glucosidase inhibitory activity. Given its lower TPC/TFC, the bulb extract is indicated to have comparatively less α-glucosidase inhibitory potential than peel extract.
Conclusion: Research confirms Allium cepa bulb extract possesses measurable antioxidant activity. However, its ethanolic extract demonstrates significantly lower TPC, TFC, and antioxidant capacity than onion peel extract, with aqueous bulb extract being weakest. The correlation between phenolics/flavonoids and α-glucosidase inhibition further suggests the bulb extract has relatively less potential in this specific activity compared to peel extracts. This underscores the difference in bioactive potency between onion parts.

In-vitro Antifungal Efficacy of Allium cepa Bulb Extract

Singh, B. K., et al. International Education And Research Journal 3.9 (2017).

Allium cepa bulb, recognized globally as a traditional nutraceutical and medicinal plant, was evaluated for its antifungal properties in this study. The antifungal potential of solvent extracts of Allium cepa bulb against Aspergillus niger, Aspergillus fumigatus, Candida albicans, and Aspergillus flavus was the subject of this research. Allium cepa bulb extracts were produced with solvents including aqueous, ethanol, chloroform, and petroleum ether.
Key Results:
· Activity by Solvent: Chloroform extract demonstrated the greatest inhibition (highest with A. niger, A. fumigatus, C. albicans; moderate with A. flavus). The aqueous/Ethanol extracts had greater inhibition with all four fungi, while the petroleum ether extract had the lowest activity.
· Selectivity of Fungal Inhibition: The extracts were consistently effective against A. niger, A. fumigatus, C. albicans, and A. flavus, indicating broad-spectrum potential.
· Bioactive Determinants: Antifungal activity aligned with the presence of phenolic compounds (e.g., quercetin, kaempferol) and sulfur-based compounds (e.g., allicin, thiosulfonates) from earlier findings. Dose-dependent growth inhibition indicated these compounds as primary efficacy drivers.