6-Bromo-2H-benzo[b][1,4]oxazin-3(4H)-one

• CAS: 24036-52-0
• Catalog Number: ACM24036520
• Category: Bromine Series
• Molecular Weight: 228.04
• Molecular Formula: C8H6BrNO2

Synthetic Use

Upstream Synthesis Route 1

• 40925-68-6
• 79-04-9

• 24036-52-0

Reference: [1] Journal of Medicinal Chemistry, 2015, vol. 58, # 1, p. 333 - 346

Upstream Synthesis Route 2

• 698982-99-9

• 24036-52-0

Reference: [1] Patent: WO2008/150848, 2008, A1, . Location in patent: Page/Page column 134-135

Upstream Synthesis Route 3

• 528892-33-3

• 24036-52-0

Reference: [1] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 17, p. 5912 - 5949
[2] Patent: WO2003/97639, 2003, A1, . Location in patent: Page/Page column 19
[3] Patent: WO2007/77961, 2007, A2, . Location in patent: Page/Page column 226-227

Upstream Synthesis Route 4

• 40925-68-6
• 79-04-9

• 24036-52-0

Reference: [1]George, Dawn M.; Breinlinger, Eric C.; Argiriadi, Maria A.; Zhang, Yang; Wang, Jianfei; Bansal-Pakala, Pratima; Duignan, David B.; Honore, Prisca; Lang, Qingyu; Mittelstadt, Scott; Rundell, Lian; Schwartz, Annette; Sun, Jiakang; Edmunds, Jeremy J.
[Journal of Medicinal Chemistry, 2015, vol. 58, # 1, p. 333 - 346]

Downstream Synthesis Route 1

• 24036-52-0
• 74-88-4

• 24036-47-3

Reference: [1]Mazharuddin,N.; Thyagarajan,G.
[Indian Journal of Chemistry, 1969, vol. 7, p. 658 - 661]
[2]Current Patent Assignee: ASTRAZENECA PLC - WO2010/128324, 2010, A1
Location in patent: Page/Page column 70
[3]Current Patent Assignee: INCYTE CORP - US2014/171405, 2014, A1
Location in patent: Paragraph 0318

Downstream Synthesis Route 2

• 24036-52-0

• 105655-01-4

Reference: [1]Patent: WO2008/44022,2008,A1 .Location in patent: Page/Page column 29

* For details of the synthesis route, please refer to the original source to ensure accuracy.