Estrone 3-sulfate sodium salt

• CAS: 438-67-5
• Catalog Number: ACM438675
• Category: Steroidal Compounds
• Molecular Weight: 372.41
• Molecular Formula: C₁₈H₂₁NaO₅S
• Synonyms: Estrone 3-Sulfate Sodium Salt; ESTRONE 3-SULFATE SODIUM SALT
• IUPAC Name: estrone sodium sulfate
• Melting Point: 173ºC
• Density: 1.349 g/cm³
• Appearance: solid
• Exact Mass: 372.10100
• Hazard Statements: T: Toxic

Custom Q&A

What is the molecular formula of sodium estrone sulfate?

The molecular formula of sodium estrone sulfate is C18H21NaO5S.

What is the molecular weight of sodium estrone sulfate?

The molecular weight of sodium estrone sulfate is 372.4 g/mol.

What is the parent compound of sodium estrone sulfate?

The parent compound of sodium estrone sulfate is estrone sulfate.

What are the synonyms of sodium estrone sulfate?

The synonyms of sodium estrone sulfate are sodium estrone sulfate, 438-67-5, ESTRONE SODIUM SULFATE, Premarin, and Estrone 3-sulfate sodium salt.

What is the description of sodium estrone sulfate?

Sodium estrone sulfate is a steroid sulfate and an organic sodium salt that is functionally related to estrone.

How are conjugated estrogens produced?

Conjugated estrogens are produced either by isolation from the urine of pregnant mares or by synthetic generation from vegetal material. They are later conjugated to sodium sulfate to make them more water soluble.

What is the composition of the conjugated estrogen product?

The conjugated estrogen product contains a mixture of estrogens, with about 50% represented by estrone sulfate followed by 25% equilin sulfate, 15% 17-alpha-dehydroequilenin sulfate, 3% equilenin sulfate, 5% 17-alpha and 17-beta-dihydroequilenin sulfate, 2% 17-alpha-estradiolsulfate, and 3% 17-beta-estradiolsulfate. It also contains unidentified molecules with weak estrogenic activity.

When was the conjugated estrogen mixture approved for marketing in the US?

The conjugated estrogen mixture was approved for marketing in the US in 1942 based on its efficacy against certain conditions.

What is the potency of the conjugated estrogen preparation expressed in?

The potency of the conjugated estrogen preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate.

When was the currently approved product of conjugated estrogens developed?

The currently approved product of conjugated estrogens was developed by Wyeth Ayerst and FDA approved in 2003.