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Home > Products > Material & Chemicals > Micro/NanoElectronics > 2-Methylthiophenothiazine

Catalog Number
ACM7643085
Product Name
2-Methylthiophenothiazine
Structure
CAS
7643-08-5
Synonyms
2-(methylthio)-10h-phenothiazin;2-METHYLMERCAPTO PHENOTHIAZINE;2-METHYLSULFANYL-10H-PHENOTHIAZINE;2-METHYLTHIOPHENOTHIAZINE;10H-Phenothiazine, 2-(methylthio)-;Einecs 231-581-0;3-(Methylthio)phenothiazine
Molecular Formula
C13H11NS2
Molecular Weight
245.36
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1 Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells.

Kang S1, Dong SM, Kim BR, Park MS, Trink B, Byun HJ, Rho SB.

Apoptosis. 2012 Sep;17(9):989-97. doi: 10.1007/s10495-012-0717-2.

Recently, thioridazine (10-[2-(1-methyl-2-piperidyl) ethyl]-2-methylthiophenothiazine), a well-known anti-psychotic agent was found to have anti-cancer activity in cancer cells. However, the molecular mechanism of the agent in cellular signal pathways has not been well defined. Thioridazine significantly increased early- and late-stage apoptotic fraction in cervical and endometrial cancer cells, su ... Read More

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Tel:1-201-478-8534
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Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA