Kang S1, Dong SM, Kim BR, Park MS, Trink B, Byun HJ, Rho SB.
Apoptosis. 2012 Sep;17(9):989-97. doi: 10.1007/s10495-012-0717-2.Recently, thioridazine (10-[2-(1-methyl-2-piperidyl) ethyl]-2-methylthiophenothiazine), a well-known anti-psychotic agent was found to have anti-cancer activity in cancer cells. However, the molecular mechanism of the agent in cellular signal pathways has not been well defined. Thioridazine significantly increased early- and late-stage apoptotic fraction in cervical and endometrial cancer cells, su ... Read More