WR99210

• CAS: 47326-86-3
• Catalog Number: ACM47326863
• Category: Inhibitors
• Molecular Weight: 394.68
• Molecular Formula: C14H18Cl3N5O2
• Description: WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine (HY-18062)-resistant P. falciparum strains) as well as T. gondii.
• Synonyms: 1,6-Dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine
• IUPAC Name: 6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine
• Canonical SMILES: CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C
• InChI Key: MJZJYWCQPMNPRM-UHFFFAOYSA-N
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; *The compound is unstable in solutions, freshly prepared is recommended..
• Exact Mass: 393.05300
• H-Bond Acceptor: 7
• H-Bond Donor: 2
• Shipping: Can be shipped at room temperature, where not in use may vary.