S14506 HCl

• CAS: 286369-38-8
• Catalog Number: ACM286369388
• Category: Agonists
• Molecular Weight: 443.95
• Molecular Formula: C24H27ClFN3O2
• Description: S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity.
• Synonyms: S 14506 HCl; S14506HCl; S14506 HCl; S-14506
• IUPAC Name: 4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride
• Canonical SMILES: O=C(NCCN1CCN(C2=C3C=C(OC)C=CC3=CC=C2)CC1)C4=CC=C(F)C=C4.[H]Cl
• InChI: InChI=1S/C24H26FN3O2.ClH/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19;/h2-10,17H,11-16H2,1H3,(H,26,29);1H
• InChI Key: HWLZKPKZVOLFGK-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 135722-25-7 (free base); 286369-38-8 (HCl)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 64.93; H, 6.13; Cl, 7.99; F, 4.28; N, 9.47; O, 7.21
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).