Rilpivirine-d6

• CAS: 1312424-26-2
• Catalog Number: ACM1312424262
• Category: Inhibitors
• Molecular Weight: 372.46
• Molecular Formula: C₂₂H₁₂D₆N₆
• Description: Rilpivirine-d6 is the deuterium labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV.
• Synonyms: 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-(dimethyl-d6)phenyl]amino]-2-pyrimidinyl]amino]benzonitrile
• IUPAC Name: 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-bis(trideuteriomethyl)anilino]pyrimidin-2-yl]amino]benzonitrile
• Canonical SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N
• InChI Key: YIBOMRUWOWDFLG-XDMLVRQJSA-N
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Exact Mass: 372.19700
• H-Bond Acceptor: 6
• H-Bond Donor: 2
• Shipping: Can be shipped at room temperature, where not in use may vary.