Pyridoxal phosphate

• CAS: 54-47-7
• Catalog Number: ACM54477
• Category: Inhibitors
• Molecular Weight: 247.14
• Molecular Formula: C₈H₁₀NO₆P
• Description: Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
• Synonyms: PYRIDOXAL-5-PHOSPHORIC ACID;PYRIDOXAL 5-MONOPHOSPHATE;CODECARBOXYLASE;3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyd;3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyd;apolonb(sub6);apolonb6;biosechs
• Melting Point: 140-143°C
• Appearance: powder
• Safety Description: 22-24/25

Custom Q&A

What is the molecular formula of pyridoxal phosphate?

The molecular formula of pyridoxal phosphate is C8H10NO6P.

What is the molecular weight of pyridoxal phosphate?

The molecular weight of pyridoxal phosphate is 247.14 g/mol.

What is the IUPAC name of pyridoxal phosphate?

The IUPAC name of pyridoxal phosphate is (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate.

What is the InChI of pyridoxal phosphate?

The InChI of pyridoxal phosphate is InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14).

How many hydrogen bond donor counts does pyridoxal phosphate have?

Pyridoxal phosphate has 3 hydrogen bond donor counts.

How many hydrogen bond acceptor counts does pyridoxal phosphate have?

Pyridoxal phosphate has 7 hydrogen bond acceptor counts.

What is one of the synonyms for pyridoxal phosphate?

One of the synonyms for pyridoxal phosphate is pyridoxal 5-phosphate.

What is the role of pyridoxal phosphate in the body?

Pyridoxal phosphate serves as a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids, and aminolevulinic acid.

What is the active form of vitamin B6 that pyridoxal phosphate serves as?

Pyridoxal phosphate is the active form of vitamin B6.

What is one of the drug uses of pyridoxal phosphate?

Pyridoxal phosphate is used in Medicure's MC-1 drug as a cardio-protectant to reduce heart damage during artery blockages and bypass surgery.

Synthetic Use

Upstream Synthesis Route 1

• 53-91-8

• 54-85-3
• 54-47-7

Reference: [1] Helvetica Chimica Acta, 1998, vol. 81, # 5, p. 837 - 844

Upstream Synthesis Route 2

• 529-96-4

• 54-47-7

Reference: [1]Peterson; Sober
[Journal of the American Chemical Society, 1954, vol. 76, p. 169,172]
Peterson et al.
[Biochemical Preparations, 1953, vol. 3, p. 29,32][Journal of the American Chemical Society, 1952, vol. 74, p. 570]
[2]Wilson
[Journal of Organic Chemistry, 1957, vol. 22, p. 1120]
Wilson; Harris
[Journal of the American Chemical Society, 1951, vol. 73, p. 4693]
[3]Current Patent Assignee: ROCHE HOLDING AG - US2755284, 1955, A
[4]Current Patent Assignee: ROCHE HOLDING AG - US2755284, 1955, A