Lamivudine

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Catalog Number
ACM134678174
Product Name
Lamivudine
Structure
Structure
CAS
134678-17-4
Category
Inhibitors
Description
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS.
Synonyms
(-)-BCH-189;(-)-BETA-L-2,3-DIDEOXY-3-THIACYTIDINE;(-)-B-L-2,3-DIDEOXY-3-THIACYTIDINE;(2r-cis)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1h)-pyrimidinone;2-deoxy-3-thiacytidine;4-AMINO-1-((2R,5S)-2-HYDROXYMETHYL-[1,3]OXATHIOLAN-5-YL)-1H-PYRIMIDIN-2-ONE;3TC;3-THIA-2,3-DIDEOXYCYTIDINE
Molecular Weight
229.26
Molecular Formula
C8H11N3O3S
Canonical SMILES
OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1
Melting Point
177°C
Appearance
Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Shipping
Can be shipped at room temperature, where not in use may vary.
Supplemental Hazard Statements
H361-H225-H301+H311+H331-H370
Symbol
GHS02,GHS06,GHS08
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