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Catalog Number
ACM623336
Product Name
Glycine ethyl ester hydrochloride
Structure
CAS
623-33-6
Category
Amino Acids
Synonyms
GEE, Ethyl glycinate hydrochloride
Molecular Weight
139.58
Molecular Formula
NH2CH2COOC2H5 · HCl
Canonical SMILES
Cl.CCOC(=O)CN
InChI
1S/C4H9NO2.ClH/c1-2-7-4(6)3-5;/h2-3,5H2,1H3;1H
InChI Key
TXTWXQXDMWILOF-UHFFFAOYSA-N
Melting Point
145-146 ℃(lit.)
Application
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide (EDC) for carboxyl-footprinting studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH.