Fosinopril

• CAS: 98048-97-6
• Catalog Number: ACM98048976
• Category: Inhibitors
• Molecular Weight: 563.66
• Molecular Formula: C₃₀H₄₆NO₇P
• Description: Fosinopril (SQ28555 free acid) is the ester proagent of angiotensin-converting enzyme (ACE) inhibitor with an IC50 value of 0.18 μM. Fosinopril demonstrates a non-competitive inhibition effect on ACE activity with an Ki value of 1.675 μM.
• Synonyms: Fosinopril
• SMILES: O=C(O)[C@H]1N(C(C[P@@](CCCCC2=CC=CC=C2)(O[C@H](OC(CC)=O)C(C)C)=O)=O)C[C@H](C3CCCCC3)C1
• Density: 1.173 g/cm³
• Appearance: Crystalline solid
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Shipping: Can be shipped at room temperature, where not in use may vary.

Custom Q&A

What is the PubChem CID of Fosinopril?

The PubChem CID of Fosinopril is 55891.

What is the molecular formula of Fosinopril?

The molecular formula of Fosinopril is C30H46NO7P.

What are the synonyms of Fosinopril?

The synonyms of Fosinopril include fosinopril, 98048-97-6, and Fosinopril impurity C.

What is the molecular weight of Fosinopril?

The molecular weight of Fosinopril is 563.7 g/mol.

When was Fosinopril created and modified?

Fosinopril was created on June 24, 2005, and last modified on December 30, 2023.

What is the description of Fosinopril?

Fosinopril is a phosphinate ester-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. It is used for the treatment of hypertension and heart failure. It acts as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a prodrug, and an antihypertensive agent.

What is the role of Fosinopril as an inhibitor?

Fosinopril has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor.

What is the functionally related compound of Fosinopril?

Fosinopril is functionally related to fosinoprilat.

What is the use of Fosinopril in therapy?

Fosinopril is used in the therapy of hypertension and heart failure as an angiotensin-converting enzyme (ACE) inhibitor.

What is the liver toxicity associated with Fosinopril?

Fosinopril is associated with a low rate of transient serum aminotransferase elevations during therapy and has been linked to rare instances of acute liver injury.