Fmoc-Phe(4-NO₂)-OH

• CAS: 95753-55-2
• Catalog Number: ACM95753552
• Category: Amino Acids
• Molecular Weight: 432.43
• Description: Cleavage and Deprotection Protocols for Fmoc SPPS.
• Synonyms: Fmoc-Phe(4-NO₂)-OH, N-α-Fmoc-4-nitro-L-phenylalanine
• InChI: 1S/C24H20N2O6/c27-23(28)22(13-15-9-11-16(12-10-15)26(30)31)25-24(29)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1
• InChI Key: RZRRJPNDKJOLHI-QFIPXVFZSA-N
• Melting Point: 213-223℃
• Application: Peptide synthesis.
• Assay: ≥95.0% (acidimetric); ≥97.0% (HPLC); ≥98% (TLC)
• Form: powder
• Functional Group: Fmoc
• MDL Number: MFCD00057810
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃

Synthetic Use

Upstream Synthesis Route 1

• 949-99-5
• 82911-69-1

• 95753-55-2

Reference: [1] Tetrahedron Letters, 1999, vol. 40, # 36, p. 6557 - 6560
[2] Russian Journal of Organic Chemistry, 2016, vol. 52, # 11, p. 1681 - 1685[3] Zh. Org. Khim., 2016, vol. 52, # 11, p. 1686 - 1690,5

Upstream Synthesis Route 2

• 28920-43-6
• 949-99-5

• 95753-55-2

Reference: [1]Journal of the Chemical Society. Perkin transactions II,1984,p. 1723 - 1728
[2]Bioorganic and Medicinal Chemistry Letters,1997,vol. 7,p. 715 - 718

Downstream Synthesis Route 1

• 95753-55-2

• 95753-56-3

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 1997, vol. 7, # 6, p. 715 - 718

Downstream Synthesis Route 2

• 95753-55-2

• 95753-56-3

Reference: [1] Russian Journal of Organic Chemistry, 2016, vol. 52, # 11, p. 1681 - 1685[2] Zh. Org. Khim., 2016, vol. 52, # 11, p. 1686 - 1690,5

* For details of the synthesis route, please refer to the original source to ensure accuracy.