Fmoc-homopropargylglycine

• Catalog Number: ACM942518210
• Product Name: Fmoc-homopropargylglycine
• CAS: 942518-21-0
• Category: Amino Acids
• Description: Building block for the introduction by Fmoc SPPS. of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 ℃using microwaves.
• Synonyms: Fmoc-homopropargylglycine
• IUPAC Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-ynoic acid
• Molecular Weight: 349.38
• Molecular Formula: C21H19NO4
• Canonical SMILES: C#CCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
• InChI: 1S/C21H19NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h1,4-11,18-19H,3,12-13H2,(H,22,25)(H,23,24)/t19-/m0/s1
• InChI Key: IISRBJULQYVYGV-IBGZPJMESA-N
• Density: 1.265±0.06 g/mL
• Application: Fmoc-Hpg-OH has a wide range of applications in scientific research. It can be used to synthesize peptides with desirable biological properties such as antimicrobial activity, anticancer activity, and enzyme inhibitory activity. These peptides can be used in drug discovery and development, as well as in the treatment of a wide range of diseases.
• Exact Mass: 349.131
• Form: solid
• Functional Group: acetylene
• LogP: 3.5961
• PSA: 79.12
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃