Structure

Fmoc-D-Phg-OH

CAS
111524-95-9
Catalog Number
ACM111524959
Category
Amino Acids
Molecular Weight
373.4

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Specification

Description
Standard building block of introduction of D-phenylglycine amino-acid residues by Fmoc SPPS.
Synonyms
Fmoc-D-Phg-OH, N-α-Fmoc-D-phenylglycine
InChI
1S/C23H19NO4/c25-22(26)21(15-8-2-1-3-9-15)24-23(27)28-14-20-18-12-6-4-10-16(18)17-11-5-7-13-19(17)20/h1-13,20-21H,14H2,(H,24,27)(H,25,26)/t21-/m1/s1
InChI Key
PCJHOCNJLMFYCV-OAQYLSRUSA-N
Melting Point
170-180℃
Application
Peptide synthesis.
Assay
≥96.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)
Form
powder
Functional Group
Fmoc
MDL Number
MFCD00190891
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-30℃

Upstream Synthesis Route 1

  • 470670-74-7
  • 111524-95-9

Reference: [1] Organic Letters, 2002, vol. 4, # 19, p. 3321 - 3324

Upstream Synthesis Route 2

  • 875-74-1
  • 82911-69-1
  • 111524-95-9

Reference: [1] Journal of Medicinal Chemistry, 2017, vol. 60, # 12, p. 4818 - 4839

Downstream Synthesis Route 1

  • 111524-95-9
  • 220498-02-2

Reference: [1] Synthesis, 1998, # 6, p. 837 - 841

Downstream Synthesis Route 2

  • 111524-95-9
  • 111524-97-1

Reference: [1]Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry,1998,vol. 37,p. 394 - 396

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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