Fmoc-3-chloro-L-tyrosine

• CAS: 478183-58-3
• Catalog Number: ACM478183583
• Category: Amino Acids
• Molecular Weight: 437.9
• Molecular Formula: C24H20ClNO5
• Description: Fmoc-3-chloro-L-tyrosine is a derivative of tyrosine that incorporates a fluorine group into the aromatic ring. This compound is commonly used in peptide synthesis as a building block for constructing peptides with spectroscopically detectable fluorescent labels. The Fmoc ('9-fluorenylmethyloxycarbonyl') group is a commonly used protecting group in peptide chemistry that is attached to the amino group of a peptide building block to prevent unwanted reactions during the synthesis process.
• Synonyms: Fmoc-Tyr(3-Cl)-OH, Fmoc-3-chlorotyrosine, Fmoc-3-chloro-L-tyrosine
• IUPAC Name: (2S)-3-(3-chloro-4-hydroxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC(=C(C=C4)O)Cl)C(=O)O
• InChI: 1S/C24H20ClNO5/c25-20-11-14(9-10-22(20)27)12-21(23(28)29)26-24(30)31-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-11,19,21,27H,12-13H2,(H,26,30)(H,28,29)/t21-/m0/s1
• InChI Key: KHDGYTHHDSEGNQ-NRFANRHFSA-N
• Boiling Point: 674.9℃at 760 mmHg
• Melting Point: 162-176 ℃
• Application: Fmoc-3-chloro-L-tyrosine has a range of applications in scientific experiments, including as a building block for peptide synthesis, as a fluorescent tag for protein and peptide labeling, and as a potential antibacterial and anticancer agent. The compound has also been used as a probe for studying protein-protein interactions.
• Color: White to off-white
• Exact Mass: 437.103
• Form: powder
• Functional Group: Fmoc
• LogP: 4.9709
• MDL Number: MFCD02682261
• Optical Activity: [a]D20 = -22 ± 2 ° (C=1 in DMF)
• PSA: 95.86
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Analogs of Phenylalanine and Tyrosine