Fmoc-4-amino-(1-carboxymethyl) piperidine

• CAS: 221352-82-5
• Catalog Number: ACM221352825-1
• Category: Amino Acids
• Molecular Weight: 380.4
• Molecular Formula: C22H24N2O4
• Description: 2-(4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)piperidin-1-yl)acetic acid is a synthetic compound designed as a scaffold for drug discovery. It is commonly referred to as Fmoc-Lys(Dde)-OH in the research community. The compound contains one Lysine (Lys) residue, and the abbreviation Dde stands for the protection group used to prevent the Lysine side chain from reacting during peptide synthesis.
• Synonyms: 2-(4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)piperidin-1-yl)acetic acid, Fmoc-Lys(Dde)-OH
• IUPAC Name: 2-[4-(9H-fluoren-9-ylmethoxycarbonylamino)piperidin-1-yl]acetic acid
• Canonical SMILES: C1CN(CCC1NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O
• InChI: 1S/C22H24N2O4/c25-21(26)13-24-11-9-15(10-12-24)23-22(27)28-14-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,15,20H,9-14H2,(H,23,27)(H,25,26)
• InChI Key: VLQJIWJYRZIBMP-UHFFFAOYSA-N
• Boiling Point: 604.151℃at 760 mmHg
• Flash Point: 319.179℃
• Density: 1.323 g/cm³
• Application: The versatility of Fmoc-Lys(Dde)-OH has led to its use in various scientific experiments, including peptide synthesis, drug discovery, and chemical biology. Peptides and peptidomimetics containing Fmoc-Lys(Dde)-OH have been used as probes for studying protein-protein interactions, enzyme kinetics, and receptor-ligand binding.
• Exact Mass: 380.174
• Functional Group: Fmoc
• LogP: 3.4029
• MDL Number: MFCD01321021
• PSA: 78.87
• Refractive Index: 1.649
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Heterocyclic Amino Acids