Fmoc-alpha-methyl-DL-methionine

• CAS: 147108-43-8
• Catalog Number: ACM147108438
• Category: Amino Acids
• Molecular Weight: 385.5
• Molecular Formula: C21H23NO4S
• Description: Fmoc-α-methyl-DL-methionine is a derivative of methionine, an essential amino acid that cannot be synthesized by the human body and must be obtained from dietary sources. Methionine is involved in various biological functions such as protein synthesis, methylation, and sulfur metabolism. Fmoc-α-methyl-DL-methionine is a modified form of methionine, where the alpha carbon is replaced with a methyl group and the amino group is protected with a Fmoc (9-fluorenylmethoxycarbonyl) group. The Fmoc group can be removed under mildly basic conditions, allowing for the synthesis of peptides and proteins containing Fmoc-α-methyl-DL-methionine.
• IUPAC Name: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyl-4-methylsulfanylbutanoic acid
• Canonical SMILES: CC(CCSC)(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
• InChI: 1S/C21H23NO4S/c1-21(19(23)24,11-12-27-2)22-20(25)26-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,18H,11-13H2,1-2H3,(H,22,25)(H,23,24)
• InChI Key: XVPHAVLGYDEOAF-UHFFFAOYSA-N
• Boiling Point: 614.8±55.0 ℃at 760 mmHg
• Flash Point: 325.6±31.5 ℃
• Density: 1.3±0.1 g/cm³
• Application: Fmoc-α-methyl-DL-methionine has been used in peptide and protein synthesis, where it can be incorporated as a unique building block to modulate protein structure and function. It has also been used in the development of novel biomaterials.
• Exact Mass: 385.134766
• Functional Group: Fmoc
• LogP: 4.94
• MDL Number: MFCD02682557
• Refractive Index: 1.608
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Analogs of Cysteine and Methionine
• Vapor Pressure: 0.0±1.9 mmHg at 25℃