2-Fluoroadenine

• CAS: 700-49-2
• Catalog Number: ACM700492
• Category: Inhibitors
• Molecular Weight: 153.12
• Molecular Formula: C₅H₄FN₅
• Description: 2-Fluoroadenine is a toxic purine bases. 2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for researching anticancer.
• SMILES: NC1=NC(F)=NC2=C1NC=N2
• Appearance: Solid
• Storage: 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
• Shipping: Can be shipped at room temperature, where not in use may vary.

Synthetic Use

Upstream Synthesis Route 1

• 1651-29-2

• 700-49-2

Reference: [1] Patent: CN105130989, 2017, B, . Location in patent: Paragraph 0019; 0027; 0028

Upstream Synthesis Route 2

• 143482-58-0

• 700-49-2

Reference: [1] Patent: US5180824, 1993, A,

Upstream Synthesis Route 3

• 37076-78-1

• 700-49-2

Reference: [1] Patent: WO2006/81665, 2006, A1, . Location in patent: Page/Page column 26-27

Downstream Synthesis Route 1

• 556-52-5
• 700-49-2

• 86626-06-4

Reference: [1]Journal of Heterocyclic Chemistry,1983,vol. 20,p. 295 - 299

Downstream Synthesis Route 2

• 700-49-2
• 56287-17-3

• 147048-53-1

Reference: [1]Journal of Medicinal Chemistry,1993,vol. 36,p. 119 - 125

* For details of the synthesis route, please refer to the original source to ensure accuracy.