Dyclonine hydrochloride

• Catalog Number: ACM536436
• Product Name: Dyclonine hydrochloride
• CAS: 536-43-6
• Category: Inhibitors
• Description: Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC50 of 35 µM for ALDH2 and 76 µM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local anesthetic that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain.
• Synonyms: DYCLONINE;DYCLONINE HCL;DYCLONINE HYDROCHLORIDE;LABOTEST-BB LT00771942;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride;4'-butoxy-3-piperidinopropiophenonehydrochloride
• IUPAC Name: dyclonine hydrochloride
• Molecular Weight: 325.87
• Molecular Formula: C₁₈H₂₈ClNO₂
• Boiling Point: 424.5ºC at 760 mmHg
• Melting Point: 175-176°C
• Flash Point: 210.5ºC
• Appearance: White Crystalline Solid
• Exact Mass: 325.18100
• Hazard Statements: Xn
• Packing Group: III
• Safety Description: 26-36
• Supplemental Hazard Statements: H301-H315-H318-H335
• Symbol: GHS05,GHS06
• WGK Germany: 3

Custom Q&A

What is the molecular formula of Dyclonine hydrochloride?

The molecular formula of Dyclonine hydrochloride is C18H28ClNO2.

What is the molecular weight of Dyclonine hydrochloride?

The molecular weight of Dyclonine hydrochloride is 325.9 g/mol.

What is the IUPAC name of Dyclonine hydrochloride?

The IUPAC name of Dyclonine hydrochloride is 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride.

What is the InChI key of Dyclonine hydrochloride?

The InChI key of Dyclonine hydrochloride is KNZADIMHVBBPOA-UHFFFAOYSA-N.

What is the canonical SMILES of Dyclonine hydrochloride?

The canonical SMILES of Dyclonine hydrochloride is CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl.

What is the CAS number of Dyclonine hydrochloride?

The CAS number of Dyclonine hydrochloride is 536-43-6.

What is the UNII of Dyclonine hydrochloride?

The UNII of Dyclonine hydrochloride is ZEC193879Q.

What is the NCI Thesaurus code of Dyclonine hydrochloride?

The NCI Thesaurus code of Dyclonine hydrochloride is C66875.

How does Dyclonine hydrochloride work as a local anesthetic?

Dyclonine hydrochloride reversibly binds to activated sodium channels on the neuronal membrane, decreasing its permeability to sodium ions. This leads to an increased threshold for excitation, stabilizes the membrane, inhibits depolarization, and blocks the propagation of action potential, resulting in a temporary loss of sensation in a localized area.

What is the chemical structure of Dyclonine hydrochloride?

The chemical structure of Dyclonine hydrochloride can be viewed at the following link: [https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=68304&t=l].