D-Ribose

• CAS: 50-69-1
• Catalog Number: ACM50691
• Category: COVID-19 Drug Raw Materials
• Molecular Weight: 150.13
• Molecular Formula: C5H10O5
• Synonyms: Aldehydo-D-ribose
• IUPAC Name: (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal
• SMILES: C(C(C(C(C=O)O)O)O)O
• InChI: InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
• InChI Key: PYMYPHUHKUWMLA-LMVFSUKVSA-N
• Boiling Point: 191.65 °C
• Melting Point: 88-92 °C(lit.)
• Flash Point: 180.8 °C
• Density: 1.1897 g/cm³
• Solubility: Soluble in water, insoluble in ether
• Appearance: Crystalline powder
• Storage: 2-8 °C
• Active Content: 95%
• Complexity: 104
• Exact Mass: 150.05282342
• Isomeric SMILES: C([C@H]([C@H]([C@H](C=O)O)O)O)O
• Monoisotopic Mass: 150.05282342
• pKa: 12.46±0.20(Predicted)
• Refractive Index: 1.612
• Solubility In Water: Soluble
• Specific Rotation: -21° (C=1,H2O)
• Topological Polar Surface Area: 98 Ų

Custom Q&A

What is the molecular formula of D-Ribose?

The molecular formula of D-Ribose is C5H10O5.

When was D-Ribose first created?

D-Ribose was first created on October 26, 2006.

What is the molecular weight of D-Ribose?

The molecular weight of D-Ribose is 150.13 g/mol.

What is the InChIKey of D-Ribose?

The InChIKey of D-Ribose is SRBFZHDQGSBBOR-SOOFDHNKSA-N.

How many hydrogen bond donor counts does D-Ribose have?

D-Ribose has 4 hydrogen bond donor counts.

What is the exact mass of D-Ribose?

The exact mass of D-Ribose is 150.05282342 g/mol.

What is the topological polar surface area of D-Ribose?

The topological polar surface area of D-Ribose is 90.2 Ų.

How many defined atom stereocenter counts does D-Ribose have?

D-Ribose has 3 defined atom stereocenter counts.

In which natural products can D-Ribose be found?

D-Ribose can be found in Tamarix aphylla, Streptomyces sporangiiformans, and Cannabis sativa.

What is the complexity value of D-Ribose?

The complexity value of D-Ribose is 117.

Synthetic Use

Downstream Synthesis Route 1

• 67-56-1
• 50-69-1
• 77-76-9

• 4099-85-8

Reference: [1] Journal of medicinal chemistry, 2001, vol. 44, # 18, p. 2966 - 2975
[2] Patent: JP2015/205885, 2015, A, . Location in patent: Paragraph 0443; 0444
[3] Organic Letters, 2007, vol. 9, # 6, p. 1121 - 1124

Downstream Synthesis Route 2

• 50-69-1
• 77-76-9
• 67-64-1

• 4099-85-8

Reference: [1] Patent: US2004/6007, 2004, A1, . Location in patent: Page/Page column 18; sheet 2

Downstream Synthesis Route 3

• 50-69-1
• 77-76-9

• 4099-85-8

Reference: [1] Patent: US2004/6002, 2004, A1,

Downstream Synthesis Route 4

• 50-69-1
• 24259-59-4

• 50-69-1

Reference: [1]Chemisches Zentralblatt,1914,vol. 85,p. 965

* For details of the synthesis route, please refer to the original source to ensure accuracy.