Caronic anhydride

• CAS: 67911-21-1
• Catalog Number: ACM67911211
• Category: COVID-19 Drug Raw Materials
• Molecular Weight: 140.14
• Molecular Formula: C7H8O3
• Synonyms: 6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione
• IUPAC Name: 6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione
• SMILES: CC1(C2C1C(=O)OC2=O)C
• InChI: InChI=1S/C7H8O3/c1-7(2)3-4(7)6(9)10-5(3)8/h3-4H,1-2H3
• InChI Key: QKAHKEDLPBJLFD-UHFFFAOYSA-N
• Boiling Point: 137 °C 14mmHg
• Melting Point: 53-57 °C
• Appearance: Solid

Synthetic Use

Upstream Synthesis Route 1

• 497-42-7

• 67911-21-1

Reference: [1] Journal of the American Chemical Society, 2010, vol. 132, # 33, p. 11414 - 11415
[2] Patent: WO2007/75790, 2007, A1, . Location in patent: Page/Page column 27-28
[3] Patent: WO2009/73380, 2009, A1, . Location in patent: Page/Page column 27

Upstream Synthesis Route 2

• 474429-71-5

• 67911-21-1
• 2102-46-7

Reference: [1] Russian Journal of Organic Chemistry, 2002, vol. 38, # 4, p. 511 - 518

Upstream Synthesis Route 3

• 936-87-8

• 67911-21-1

Reference: [1] Angewandte Chemie, 1984, vol. 96, # 1, p. 55 - 56
[2] Liebigs Annalen der Chemie, 1989, p. 703 - 712

Upstream Synthesis Route 4

• 936-87-8

• 67911-21-1

Reference: [1]Journal of the Chemical Society,1899,vol. 75,p. 54
Journal of the Chemical Society,1901,vol. 79,p. 753
[2]Journal of the Chemical Society,1899,vol. 75,p. 54
Journal of the Chemical Society,1901,vol. 79,p. 753
[3]Bulletin de la Societe Chimique de France,1914,vol. <4>15,p. 750
[4]Bulletin de la Societe Chimique de France,1914,vol. <4>15,p. 750

Downstream Synthesis Route 1

• 67911-21-1
• 56613-80-0

• 86331-39-7

Reference: [1]Chemistry Letters,1983,p. 385 - 388

* For details of the synthesis route, please refer to the original source to ensure accuracy.