Cambinol

• CAS: 14513-15-6
• Catalog Number: ACM14513156
• Category: Inhibitors
• Molecular Weight: 360.43
• Molecular Formula: C₂₁H₁₆N₂O₂S
• Description: Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
• Synonyms: cambinol, NSC112546, NSC-112546, SIRT1/2 Inhibitor IV, Cambinol, 14513-15-6, 5-(2-Hydroxy-naphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one, AC1MMYEF, NCIStruc1_001428, NCIStruc2_001159, SureCN3332758, CHEMBL491960, CTK8G3107, HMS3261K21, CCG-37240, DNC009417, NCGC00014121, NCI112546, AKOS002364304, AG-D-88787, CCG-221684
• IUPAC Name: 5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one
• InChI Key: RVNSQVIUFZVNAU-UHFFFAOYSA-N
• Boiling Point: 667ºC at 760mmHg
• Flash Point: 357.2ºC
• Density: 1.41g/cm³
• Exact Mass: 360.09300
• Hazard Statements: Xn: Harmful
• H-Bond Acceptor: 3
• H-Bond Donor: 3