Boc-Glu-OBzl

• CAS: 30924-93-7
• Catalog Number: ACM30924937
• Category: Amino Acids
• Molecular Weight: 337.37
• Description: Useful derivative for the synthesis of γ-glutamyl peptides.
• Synonyms: Boc-L-glutamic acid 1-benzyl ester
• SMILES: CC(C)(C)OC(=O)N[C@@H](CCC(O)=O)C(=O)OCc1ccccc1
• InChI: 1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1
• InChI Key: CVZUKWBYQQYBTF-ZDUSSCGKSA-N
• Melting Point: 95-99℃
• Application: Peptide synthesis.
• Assay: ≥98% (TLC)
• Beilstein: 2482076
• Biochemical Physiological Action: Boc-Glu-OBzl is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make unique peptides containing glutamate benzyl ester residues.
• Color: white to off-white
• Form: powder
• Functional Group: carboxylic acid
• MDL Number: MFCD00065568
• PubChem ID: 24892112
• Quality Level: 200
• Reaction Suitability: reaction type: Boc solid-phase peptide synthesis
• Storage Temperature: -20℃

Synthetic Use

Upstream Synthesis Route 1

• 2419-94-5
• 100-51-6

• 30924-93-7

Reference: [1] Tetrahedron, 1987, vol. 43, # 8, p. 1823 - 1826

Upstream Synthesis Route 2

• 24424-99-5
• 13030-09-6

• 30924-93-7

Reference: [1] European Journal of Medicinal Chemistry, 1992, vol. 27, # 8, p. 825 - 833

Upstream Synthesis Route 3

• 1070-19-5
• 13030-09-6

• 30924-93-7

Reference: [1]Angewandte Chemie,1972,vol. 84,p. 259
[2]Justus Liebigs Annalen der Chemie,1964,vol. 673,p. 196 - 207

Upstream Synthesis Route 4

• 24424-99-5
• 13030-09-6

• 30924-93-7

Reference: [1]European Journal of Medicinal Chemistry,1992,vol. 27,p. 825 - 833

Downstream Synthesis Route 1

• 930-21-2
• 30924-93-7

• 81721-87-1

Reference: [1] Patent: US2011/269244, 2011, A1, . Location in patent: Page/Page column

Downstream Synthesis Route 2

• 123-56-8
• 30924-93-7

• 78658-49-8

Reference: [1]Gisin, B.F.; Davis, D.G.; Borowska, Z.K.; Hall, J.E.; Kobayashi, S.
[Journal of the American Chemical Society, 1981, vol. 103, # 21, p. 6373 - 6377]

* For details of the synthesis route, please refer to the original source to ensure accuracy.