Structure

Boc-D-Pro-OH

CAS
37784-17-1
Catalog Number
ACM37784171
Category
Amino Acids
Molecular Weight
215.25

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Specification

Description
Standard building block for introduction of D-proline amino-acid residues by Boc SPPS.
Synonyms
Boc-D-Pro-OH, N-α-t.-Boc-D-proline
InChI
1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)
InChI Key
ZQEBQGAAWMOMAI-UHFFFAOYSA-N
Melting Point
>132℃
Application
Peptide synthesis.
Assay
≥98% (TLC)
Form
powder
Functional Group
Boc
MDL Number
MFCD00063226
Quality Level
200
Reaction Suitability
reaction type: Boc solid-phase peptide synthesis
Storage Temperature
2-30℃

Upstream Synthesis Route 1

  • 73365-02-3
  • 37784-17-1

Reference: [1]Journal of Organic Chemistry,1980,vol. 45,p. 2145 - 2151

Downstream Synthesis Route 1

  • 37784-17-1
  • 73365-02-3

Reference: [1] Organic Letters, 2006, vol. 8, # 23, p. 5357 - 5360

Downstream Synthesis Route 2

  • 37784-17-1
  • 74-88-4
  • 73323-65-6

Reference: [1] Patent: WO2013/131018, 2013, A1, . Location in patent: Page/Page column 38

Downstream Synthesis Route 3

  • 37784-17-1
  • 77-78-1
  • 73323-65-6

Reference: [1] Journal of Organic Chemistry, 1999, vol. 64, # 21, p. 8014 - 8017

Downstream Synthesis Route 4

  • 186581-53-3
  • 37784-17-1
  • 73323-65-6

Reference: [1]Journal of Organic Chemistry,1980,vol. 45,p. 2145 - 2151

Downstream Synthesis Route 5

  • 3339-44-4
  • 37784-17-1
  • 157016-28-9

Reference: [1]Journal of Organic Chemistry,1994,vol. 59,p. 2437 - 2446
[2]Chemical Communications,2008,p. 4174 - 4176

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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