Boc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid

• CAS: 187039-57-2
• Catalog Number: ACM187039572-1
• Category: Amino Acids
• Molecular Weight: 231.2
• Molecular Formula: C10H17NO5
• Description: (2S,3S)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid is a chiral, α-amino acid that is used extensively in organic synthesis due to its intriguing physical and chemical properties. The compound is also known as Boc-D-3-hydroxyproline, Boc-D-Hyp-OH or D-3-Hyp.
• Synonyms: (2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• IUPAC Name: (2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• Canonical SMILES: CC(C)(C)OC(=O)N1CCC(C1C(=O)O)O
• InChI: 1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-4-6(12)7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m0/s1
• InChI Key: JLDHXHPQMBNKMC-BQBZGAKWSA-N
• Boiling Point: 390.9±42.0 ℃at 760 mmHg
• Flash Point: 190.2±27.9 ℃
• Density: 1.3±0.1 g/cm³
• Application: The compound can be used for developing novel drug candidates, as a chiral building block in the synthesis of biologically active compounds, and as proline isomers in peptide chemistry and protein applications. Studies also show that it can inhibit the activity of protease enzymes and is used in peptide synthesis.
• Exact Mass: 231.110672
• Functional Group: Boc
• HS Code: 2933990090
• LogP: -0.54
• MDL Number: MFCD04974546
• PSA: 87.07
• Refractive Index: 1.531
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Analogs of Proline
• Vapor Pressure: 0.0±2.0 mmHg at 25℃