Benzaldehyde,p-fluoro-,oxime

• CAS: 459-23-4
• Catalog Number: ACM459234
• Category: Other Products
• Molecular Weight: 139.127
• Molecular Formula: C₇H₆FNO
• Synonyms: p-fluorobenzaldehydeoxime;p-fluoro-benzaldehydoxime;4-FLUOROBENZALDOXIME;4-FLUOROBENZALDEHYDE OXIME;syn-4-fluorobenzaldoxime
• IUPAC Name: (NZ)-N-[(4-fluorophenyl)methylidene]hydroxylamine
• InChI Key: FSKSLWXDUJVTHE-UITAMQMPSA-N
• Boiling Point: 194.9ºC at 760mmHg
• Melting Point: 82-85ºC
• Flash Point: 71.7ºC
• Density: 1.14g/cm³
• Exact Mass: 139.04300
• Hazard Statements: Xi,Xn
• H-Bond Acceptor: 3
• H-Bond Donor: 1
• Safety Description: S26

Synthetic Use

Upstream Synthesis Route 1

• 459-57-4

• 459-23-4

Reference: [1]Current Patent Assignee: VERTEX PHARMACEUTICALS (OLD) - WO2004/22555, 2004, A1
Location in patent: Page 19

Downstream Synthesis Route 1

• 459-23-4
• 107-19-7

• 206055-89-2

Reference: [1] Bulletin of the Korean Chemical Society, 2012, vol. 33, # 12, p. 4227 - 4230

Downstream Synthesis Route 2

• 459-23-4
• 6175-54-8

• 206055-89-2

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 12, p. 2674 - 2677

Downstream Synthesis Route 3

• 459-23-4

• 206055-89-2

Reference: [1] Synthesis, 2002, # 12, p. 1663 - 1668

Downstream Synthesis Route 4

• 459-23-4

• 42202-95-9

Reference: [1]Journal of Medicinal Chemistry,2003,vol. 46,p. 284 - 302

Downstream Synthesis Route 5

• 459-23-4

• 1194-02-1

Reference: [1]Synthetic Communications,1999,vol. 29,p. 1741 - 1745

* For details of the synthesis route, please refer to the original source to ensure accuracy.