4-Fluoroindole-2-carboxylic acid

• CAS: 399-68-8
• Catalog Number: ACM399688
• Category: Indoles
• Molecular Weight: 179.15
• Molecular Formula: C9H6FNO2
• Synonyms: Indole-2-carboxylic acid, 4-fluoro- (8CI); 4-Fluoro-1H-indole-2-carboxylic acid
• Boiling Point: 422.2 °C at 760 mmHg
• Flash Point: 209.1 °C
• Density: 1.51 g/cm³

Synthetic Use

Upstream Synthesis Route 1

• 7593-91-1

• 399-68-8

Reference: [1] Journal of Medicinal Chemistry, 1988, vol. 31, # 5, p. 944 - 948
[2] Patent: US2014/66453, 2014, A1, . Location in patent: Paragraph 0184-0185

Upstream Synthesis Route 2

• 113162-36-0

• 399-68-8

Reference: [1] Canadian Journal of Chemistry, 2007, vol. 85, # 4, p. 283 - 292
[2] Nucleosides, Nucleotides and Nucleic Acids, 2007, vol. 26, # 8-9, p. 869 - 871

Upstream Synthesis Route 3

• 769-10-8
• 95-92-1

• 399-68-8

Reference: [1]Journal of the Chemical Society,1955,p. 1283,1284
[2]Patent: US6335360,2002,B1 .Location in patent: Page column 20

Upstream Synthesis Route 4

• 7593-91-1

• 399-68-8

Reference: [1]Journal of Medicinal Chemistry,1988,vol. 31,p. 944 - 948
[2]Patent: US2014/66453,2014,A1 .Location in patent: Paragraph 0184-0185

Downstream Synthesis Route 1

• 399-68-8

• 387-43-9

Reference: [1] Canadian Journal of Chemistry, 2007, vol. 85, # 4, p. 283 - 292
[2] Nucleosides, Nucleotides and Nucleic Acids, 2007, vol. 26, # 8-9, p. 869 - 871
[3] Journal of the Chemical Society, 1955, p. 1283,1284

Downstream Synthesis Route 2

• 399-68-8

• 387-43-9

Reference: [1]Canadian Journal of Chemistry,2007,vol. 85,p. 283 - 292
[2]Nucleosides, nucleotides and nucleic acids,2007,vol. 26,p. 869 - 871
[3]Journal of the Chemical Society,1955,p. 1283,1284

* For details of the synthesis route, please refer to the original source to ensure accuracy.