4-Amino-3,5-Di-2-Pyridyl-4H-1,2,4-Triazole

• CAS: 1671-88-1
• Catalog Number: ACM1671881
• Category: Other Products
• Molecular Weight: 238.25
• Molecular Formula: C12H10N6
• IUPAC Name: 3,5-dipyridin-2-yl-1,2,4-triazol-4-amine
• InChI: InChI=1S/C12H10N6/c13-18-11(9-5-1-3-7-14-9)16-17-12(18)10-6-2-4-8-15-10/h1-8H,13H2
• InChI Key: VHRKXLULSZZZQT-UHFFFAOYSA-N
• Complexity: 247
• CompoundIs Canonicalized: Yes
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Exact Mass: 238.09669434g/mol
• Formal Charge: 0
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Isotope Atom Count: 0
• Monoisotopic Mass: 238.09669434g/mol
• Rotatable Bond Count: 2
• Topological Polar Surface Area: 82.5Ų
• Undefined Atom Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• XLogP3: 0.4

Custom Reviews

June 16, 2023

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Intermediate of drug synthesis
The purity of anti-tuberculosis drugs prepared by 4-amino-3,5-di-2-pyridyl-4H-1,2,4-triazole is very high.

Synthetic Use

Upstream Synthesis Route 1

• 100-70-9

• 1671-88-1

Reference: [1]Tetrahedron Letters,2000,vol. 41,p. 1539 - 1541

Downstream Synthesis Route 1

• 1671-88-1

• 1671-85-8

Reference: [1]Inorganic Chemistry,2017,vol. 56,p. 15259 - 15270
[2]Journal of Heterocyclic Chemistry,2002,vol. 39,p. 93 - 96
[3]Chemical Communications,2012,vol. 48,p. 6229 - 6231

Downstream Synthesis Route 2

• 696-59-3
• 1671-88-1

• 151194-66-0

Reference: [1]Journal of Organometallic Chemistry,2021,vol. 954-955
[2]European Journal of Inorganic Chemistry,2009,p. 1172 - 1180
[3]European Journal of Inorganic Chemistry,2006,p. 573 - 589

* For details of the synthesis route, please refer to the original source to ensure accuracy.