1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid,pinacol ester

• CAS: 864754-18-7
• Catalog Number: ACM864754187
• Category: Other Products
• Molecular Weight: 307.2
• Molecular Formula: C₁₅H₂₆BN₃O₃
• Synonyms: FS000540, 1-(2-Morpholinoethyl)-1H-pyrazol-4-boronic acid pinacol ester, 864754-18-7
• IUPAC Name: 4-[2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]ethyl]morpholine
• InChI Key: FBAPTUAEBQMVEY-UHFFFAOYSA-N
• Boiling Point: 440.6ºC at 760 mmHg
• Flash Point: 220.3ºC
• Density: 1.15g/cm³
• Exact Mass: 307.20700
• H-Bond Acceptor: 6
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 73183-34-3

• 864754-18-7

Reference: [1] Patent: WO2014/162039, 2014, A1, . Location in patent: Page/Page column 35; 36

Upstream Synthesis Route 2

• 269410-08-4
• 3647-69-6

• 864754-18-7

Reference: [1] Patent: WO2017/178416, 2017, A1, . Location in patent: Page/Page column 116

Upstream Synthesis Route 3

• 89583-07-3
• 269410-08-4

• 864754-18-7

Reference: [1] Journal of Medicinal Chemistry, 2009, vol. 52, # 24, p. 7934 - 7937

Upstream Synthesis Route 4

• 89583-07-3
• 269410-08-4

• 864754-18-7

Reference: [1]Journal of Medicinal Chemistry,2009,vol. 52,p. 7934 - 7937

Downstream Synthesis Route 1

• 864754-18-7
• 1309774-04-6

• 1422126-22-4

Reference: [1]Current Patent Assignee: FUJIFILM HOLDINGS CORP. - EP2727920, 2014, A1
Location in patent: Paragraph 0589-0590
[2]Current Patent Assignee: FUJIFILM HOLDINGS CORP. - US2015/322063, 2015, A1
Location in patent: Paragraph 1398; 1399; 1400

* For details of the synthesis route, please refer to the original source to ensure accuracy.