1H-Pyrrolo[2,3-b]pyridine,4-chloro-1-[tris(1-methylethyl)silyl]-

Name: 1H-Pyrrolo[2,3-b]pyridine,4-chloro-1-[tris(1-methylethyl)silyl]-
SKU: ACM651744488
Rating: 5 (1 reviews)

CAS

651744-48-8

Catalog Number

ACM651744488

Category

Other Products

Molecular Weight

308.921600 [g/mol]

Molecular Formula

C₁₆H₂₅ClN₂Si

COA MSDS SDS Spec Sheet

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Specification

Synonyms

1H-Pyrrolo[2,3-b]pyridine, 4-chloro-1-[tris(1-methylethyl)silyl]-;4-Chloro-1-(triisopropylsilyl)-7-azaindole

IUPAC Name

(4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane

SMILES

CC(C)[Si](C(C)C)(C(C)C)N1C=CC2=C(C=CN=C21)Cl

InChI Key

HSMLARVFJADZQS-UHFFFAOYSA-N

Boiling Point

320.543ºC at 760 mmHg

Flash Point

147.659ºC

Density

1.058g/cm³

Exact Mass

308.14800

H-Bond Acceptor

H-Bond Donor

Downstream Synthesis Route 1

541-41-3
651744-48-8

885500-55-0

Reference: [1] Chemical and Pharmaceutical Bulletin, 2015, vol. 63, # 5, p. 341 - 353

Downstream Synthesis Route 2

651744-48-8

98549-88-3

Reference: [1] Tetrahedron Letters, 2004, vol. 45, # 11, p. 2317 - 2319

Downstream Synthesis Route 3

651744-48-8

885500-55-0

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 3, p. 693 - 698

Downstream Synthesis Route 4

651744-48-8

685513-96-6

Reference: [1]Current Patent Assignee: SYROS PHARMACEUTICALS INC - WO2018/191587, 2018, A1
Location in patent: Paragraph 0155; 0157
[2]L'Heureux, Alexandre; Thibault, Carl; Ruel, Réjean
[Tetrahedron Letters, 2004, vol. 45, # 11, p. 2317 - 2319]
[3]Current Patent Assignee: PFIZER INC - WO2009/89352, 2009, A1
Location in patent: Page/Page column 54

Downstream Synthesis Route 5

651744-48-8

685513-94-4

Reference: [1]Current Patent Assignee: IKENA ONCOLOGY INC - WO2022/51568, 2022, A1
Location in patent: Paragraph 0783
[2]Current Patent Assignee: IKENA ONCOLOGY INC - WO2022/51568, 2022, A1
Location in patent: Paragraph 0783
[3]L'Heureux, Alexandre; Thibault, Carl; Ruel, Réjean
[Tetrahedron Letters, 2004, vol. 45, # 11, p. 2317 - 2319]
[4]Current Patent Assignee: REDX PHARMA PLC - WO2016/55790, 2016, A1
Location in patent: Paragraph 00172

* For details of the synthesis route, please refer to the original source to ensure accuracy.

Please kindly note that our products are for research use only.

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