Structure

Irigenin

CAS
548-76-5
Catalog Number
ACM548765-1
Category
Inhibitors
Molecular Weight
360.31
Molecular Formula
C18H16O8

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Specification

Description
Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells.
Canonical SMILES
O=C1C(C2=CC(OC)=C(OC)C(O)=C2)=COC3=CC(O)=C(OC)C(O)=C13
Appearance
Solid
Storage
4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
PlantsIridaceaeBelamcanda chinensis (Linn.) Redouté
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