Fmoc-Arg(Me)2-OH (asymmetrical)

Name: Fmoc-Arg(Me)2-OH (asymmetrical)
SKU: ACM268564109-1
Rating: 5 (1 reviews)

CAS

268564-10-9

Catalog Number

ACM268564109-1

Category

Amino Acids

Molecular Weight

424.5

Molecular Formula

C23H28N4O4

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Specification

Description

Fmoc-Arg(Me)2-OH is a peptide derivative that consists of two methylated arginines (Me) with an N-terminal Fluorenylmethyloxycarbonyl (Fmoc) group. The Fmoc group is a protective group that is commonly used in peptide synthesis to protect the N-terminus of amino acids from unwanted reactions. Arginine is an amino acid that plays an essential role in protein synthesis, and its importance in biological functions has been well established. The introduction of the Me modification to the arginine molecule has led to significant developments in peptide synthesis.

IUPAC Name

(2S)-5-[[amino(dimethylamino)methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid

Canonical SMILES

CN(C)C(=NCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)N

InChI

1S/C23H28N4O4/c1-27(2)22(24)25-13-7-12-20(21(28)29)26-23(30)31-14-19-17-10-5-3-8-15(17)16-9-4-6-11-18(16)19/h3-6,8-11,19-20H,7,12-14H2,1-2H3,(H2,24,25)(H,26,30)(H,28,29)/t20-/m0/s1

InChI Key

QXAXLSMKNHJDNM-FQEVSTJZSA-N

Density

1.28 g/mL at 20 ℃(lit.)

Application

Fmoc-Arg(Me)2-OH has various applications in scientific research. This compound is commonly used in peptide synthesis and has been found to be useful in the preparation of various peptides such as antimicrobial peptides and peptide hormones. Fmoc-Arg(Me)2-OH is also used as a substrate in enzymatic assays and as a modifier in protein labeling.

Exact Mass

424.211

Functional Group

Fmoc

LogP

3.726

MDL Number

MFCD00672718

PSA

114.75

Storage Temperature

4 ℃