Structure

Ethyl boc-D-pyroglutamate

CAS
144978-35-8
Catalog Number
ACM144978358
Category
Other Products
Molecular Weight
257.28
Molecular Formula
C12H19NO5

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  • Product Description
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Specification

Synonyms
1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER;Ethyl Boc-D-Pyroglutamate;(R)-5-Oxo-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester;(R)-1-Tert-butyl 2-ethyl 5-oxopyrrolidine-1,2-dicarboxylate;BOC-D-PYROGLUTAMIC ACID ETHYL ESTER
Density
1.182g/cm³

Upstream Synthesis Route 1

  • 24424-99-5
  • 7149-65-7
  • 144978-35-8

Reference: [1]Patent: US2008/9497,2008,A1 .Location in patent: Page/Page column 70-71

Downstream Synthesis Route 1

  • 144978-35-8
  • 6636-06-2

Reference: [1] Tetrahedron Letters, 1993, vol. 34, # 39, p. 6317 - 6320

Downstream Synthesis Route 2

  • 144978-35-8
  • 197142-36-2

Reference: [1] Angewandte Chemie - International Edition, 2015, vol. 54, # 45, p. 13268 - 13272[2] Angew. Chem., 2015, # 45, p. 13466 - 13470,4
[3] Patent: EP2272825, 2015, B1,

Downstream Synthesis Route 3

  • 144978-35-8
  • 361440-67-7

Reference: [1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 4, p. 1383 - 1393
[2] Patent: EP2272825, 2015, B1,
[3] Patent: EP3000893, 2016, A2,

Downstream Synthesis Route 4

  • 144978-35-8
  • 194594-23-5

Reference: [1]Tetrahedron Letters,1994,vol. 35,p. 8037 - 8040

Downstream Synthesis Route 5

  • 144978-35-8
  • 334769-80-1

Reference: [1]Journal of Medicinal Chemistry,2006,vol. 49,p. 3520 - 3535

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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