Salicyloyl chloride

Synthesis and evaluation of enantio-selective l-histidine imprinted salicylic acid functionalized resin

Monier M, El-Mekabaty A, Abdel-Latif D A
Reactive and Functional Polymers, 2018, 128: 104-113
An enantio-selective l-histidine imprinted polymeric resin was fabricated and evaluated for enantiomeric resolution of histidine racemate. The polymerizable chiral salicyloyl--histidine amide was first synthesized and anchored onto a polymeric resin network via condensation polymerization with resorcinol and formaldehyde. -histidine template molecules were then extracted out of the resin texture via alkaline hydrolysis of the amide bond using sodium hydroxide. The synthetic steps were monitored by means of instrumental techniques including elemental analysis; mass spectra along with both Fouri...