Yum K1, Ahn JH, McNicholas TP, Barone PW, Mu B, Kim JH, Jain RM, Strano MS.
ACS Nano. 2012 Jan 24;6(1):819-30. doi: 10.1021/nn204323f. Epub 2011 Dec 16.We describe the high-throughput screening of a library of 30 boronic acid derivatives to form complexes with sodium cholate suspended single-walled carbon nanotubes (SWNTs) to screen for their ability to reversibly report glucose binding via a change in SWNT fluorescence. The screening identifies 4-cyanophenylboronic acid which uniquely causes a reversible wavelength red shift in SWNT emission. The results also identify 4-chlorophenylboronic acid which demonstrates a turn-on fluorescence response when complexed with SWNTs upon glucose binding in the physiological range of glucose concentration. Read More