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tert-Butyl cinnamate98 | CAS Number: 7042-36-6

Catalog Number
ACM7042366
Product Name
tert-Butyl cinnamate98
Structure
CAS Number
7042-36-6
Synonyms
TERT-BUTYL CINNAMATE98;TERT-BUTYL CINNAMATE, 99.5%
Molecular Weight
204.26494
Molecular Formula
C13H16O2
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1Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.

Fu DJ1, Zhang L1, Song J1, Mao RW1, Zhao RH1, Liu YC1, Hou YH1, Li JH1, Yang JJ1, Jin CY1, Li P1, Zi XL2, Liu HM1, Zhang SY3, Zhang YB4.

Eur J Med Chem. 2016 Dec 14;127:87-99. doi: 10.1016/j.ejmech.2016.12.027. [Epub ahead of print]

A series of novel formononetin-dithiocarbamate derivatives were designed, synthesized and evaluated for antiproliferative activity against three selected cancer cell line (MGC-803, EC-109, PC-3). The first structure-activity relationship (SAR) for this formononetin-dithiocarbamate scaffold is explored in this report with evaluation of 14 variants of the structural class. Among these analogues, tert-butyl 4-(((3-((3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)propyl)thio)carbonothioyl)piperazine-1-carboxylate (8i) showed the best inhibitory activity against PC-3 cells (IC50 = 1. Read More

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Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA