2-Benzoxazolinone

• Catalog Number: ACM59494-1
• Product Name: 2-Benzoxazolinone
• CAS: 59-49-4
• Category: Inhibitors
• Description: 2-Benzoxazolinone is an anti-leishmanial agent with an LC50 of 40 μg/mL against L. donovani. A building block in chemical synthesis. 1,3-Benzoxazol-2(3H)-one derivatives have antimicrobial activity against a selection of Gram-positive, Gram-negative bacteria and yeasts. Derivatives as anti-quorum sensing agent.
• Synonyms: 2,3-Dihydro-2-oxo-1,3-benzoxazole
• Molecular Weight: 135.12
• Molecular Formula: C7H5NO2
• Canonical SMILES: O=C1OC2=CC=CC=C2N1
• InChI: InChI=1S/C7H5NO2/c9-7-8-5-3-1-2-4-6(5)10-7/h1-4H,(H,8,9)
• InChI Key: ASSKVPFEZFQQNQ-UHFFFAOYSA-N
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Complexity: 158
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 0
• Exact Mass: 135.032028402
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Monoisotopic Mass: 135.032028402
• Physical State: Powder
• Rotatable Bond Count: 0
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsGramineaeSecale cereale
• Topological Polar Surface Area: 38.3 Ų

Custom Q&A

What is the molecular formula of 2-Benzoxazolinone?

The molecular formula of 2-Benzoxazolinone is C7H5NO2.

What is the chemical property of 2-Benzoxazolinone?

2-Benzoxazolinone is a light beige to brown-grey powder that is insoluble in water but soluble in benzene, chlorobenzene, and other solvents.

What is the melting point of 2-Benzoxazolinone?

The melting point of 2-Benzoxazolinone is 137-139 °C.

How is 2-Benzoxazolinone synthesized?

2-Benzoxazolinone can be synthesized by reacting o-aminophenol, urea, and solvent chlorobenzene in a reaction kettle protected with nitrogen.

What is one of the uses of 2-Benzoxazolinone?

2-Benzoxazolinone is used in the study of the antioxidant activity of heterocyclic chalcones.

What are some safety statements associated with 2-Benzoxazolinone?

Safety statements associated with 2-Benzoxazolinone include 36-24/25-26.

How is 2-Benzoxazolinone stored?

2-Benzoxazolinone is sealed in dry storage at room temperature.

What is the purpose of the synthesis references provided for 2-Benzoxazolinone?

The synthesis references provided for 2-Benzoxazolinone are for the study and development of the inhibitors of nitric oxide synthases.

What type of chemical reactivity does 2-Benzoxazolinone exhibit?

2-Benzoxazolinone is chemically active and can undergo reactions such as methylation and chlorine substitution.

What is one of the toxicological properties of 2-Benzoxazolinone?

2-Benzoxazolinone is moderately toxic by ingestion and can emit toxic fumes of NOx when heated to decomposition.