Dehydrocorydaline nitrate

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Catalog Number
ACM13005099
Product Name
Dehydrocorydaline nitrate
Structure
Structure
CAS
13005-09-9
Category
Inhibitors
Description
Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities.. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.
Synonyms
Hydrocortisonenitrate
Molecular Weight
428.4
Molecular Formula
C22H24N2O7
Canonical SMILES
[O-][N+]([O-])=O.CC1=C(C=CC(OC)=C2OC)C2=C[N+]3=C1C4=CC(OC)=C(OC)C=C4CC3
InChI
InChI=1S/C22H24NO4.NO3/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23;2-1(3)4/h6-7,10-12H,8-9H2,1-5H3;/q+1;-1
InChI Key
CZZFYGAXGATDNG-UHFFFAOYSA-N
Melting Point
240 °C
Appearance
Solid
Storage
4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Complexity
522
Covalently-Bonded Unit Count
2
Defined Atom Stereocenter Count
0
Exact Mass
428.15835111
Heavy Atom Count
31
Hydrogen Bond Acceptor Count
7
Hydrogen Bond Donor Count
0
Monoisotopic Mass
428.15835111
Physical State
Powder
Rotatable Bond Count
4
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
Plantsother families
Topological Polar Surface Area
104 Ų
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