Irinotecan hydrochloride

• Catalog Number: ACM100286906
• Product Name: Irinotecan hydrochloride
• CAS: 100286-90-6
• Category: Inhibitors
• Description: Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer.
• Synonyms: Camptothecin II
• Molecular Weight: 623.1
• InChI: InChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H/t33-;/m0./s1
• InChI Key: GURKHSYORGJETM-WAQYZQTGSA-N
• Melting Point: 250-256 °C
• Complexity: 1200
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 1
• Exact Mass: 622.2558127
• Heavy Atom Count: 44
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 2
• Isomeric SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
• Monoisotopic Mass: 622.2558127
• Physical State: Powder
• Rotatable Bond Count: 5
• Topological Polar Surface Area: 113 Ų