Propylene Glycol

• Catalog Number: ACM57556
• Product Name: Propylene Glycol
• CAS: 57-55-6
• Category: Main Products
• Description: Modified alcohol (1,2-propanediol), metabolized to lactic acid in the body.
• Synonyms: Propyleneglycol manufacturer
• IUPAC Name: Propane-1,2-diol
• Molecular Weight: 76.09
• Molecular Formula: C3H8O2
• Canonical SMILES: CC(CO)O
• InChI: InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• InChI Key: DNIAPMSPPWPWGF-UHFFFAOYSA-N
• Boiling Point: 187 °C(lit.)
• Melting Point: -60 °C(lit.)
• Flash Point: 225 °F
• Density: 1.036 g/mL at 25 °C(lit.)
• Solubility: Soluble in water, ethanol, acetone
• Appearance: Liquid
• Application: All kinds of skin care products, hair care products, color cosmetics, soaps (glycerin soap).
• Storage: 5-30 °C
• Autoignition Temperature: 700 °F (USCG, 1999);700 °F (371 °C);420 °C
• Color/Form: Colorless viscous liquid
• Complexity: 20.9
• Composition: Propylene glycol
• Covalently-Bonded Unit Count: 1
• Decomposition: When heated to decomposition it emits acrid smoke and irritating fumes.
• Defined Atom Stereocenter Count: 0
• EC Number: 200-338-0;200-338-0;613-293-0
• Exact Mass: 76.052429494
• Features And Benefits: Effective humectant and wetting agent preventing water loss in products and in the skinIncreases skin permeability of active ingredients as it penetrates into the outermost skin layersEmollient and lubricant propertiesExcellent solubilizer of other ingredientsIncreases spreading of creams
• Formal Charge: 0
• H-Bond Acceptor: 2
• H-Bond Donor: 2
• Heat of Vaporization: 168.6 cal/g at BP
• Heavy Atom Count: 5
• HS Code: 2905320000
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• ICSC Number: 0321
• LogP: -0.92 (LogP);-0.92;log Kow = -0.92;-0.92;-0.92
• Monoisotopic Mass: 76.052429494
• NSC Number: 69860;35749;35748;35747
• Odor: Practically odorless
• Other Experimental: Specific heat: 0.590 cal/g at 20 °C; hygroscopic;Heat of vaporization = 15.4 kcal/mol at 25 °C; heat of formation = -116.1 kcal/mol at 25 °C (liquid); heat capacity = 45.1 kcal/mol at 20 °C; viscosity = 56.0 cP at 20 °C; surface tension = 36.51 dyne/cm at 25 °C;BP: 88-90 °C at 12 mm Hg; 187-189 °C at 760 mm Hg. Specific optical rotation: -15 deg at 20 °C /l-form/;BP: 95-96 °C at 14 mm Hg; Specific optical rotation: +15 (neat) deg at 20 °C; Density: 1.04 at 25 °C/4/ degC /d-form/;Henry's Law constant = 1.3X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 1.2X10-11 cu cm/molec-sec at 25 °C
• Physical State: Viscous liquid
• pKa: 14.49±0.20(Predicted)
• Refractive Index: n20/D 1.432(lit.)
• Rotatable Bond Count: 1
• RTECS Number: TY2000000
• Stability: At cool temperatures, propylene glycol is stable in a well-closed container, but at high temperatures, in the open, it tends to oxidize, giving rise to products such as propionaldehyde, lactic acid, pyruvic acid, and acetic acid. Propylene glycol is chemically stable when mixed with ethanol (95%), glycerin, or water; aqueous solutions may be sterilized by autoclaving.
• Storage Conditions: 5-30 °C
• Topological Polar Surface Area: 40.5 Ų
• Vapor Density: 2.62 (NTP, 1992) (Relative to Air);Relative vapor density (air = 1): 2.6;2.62
• Vapor Pressure: 0.08 mm Hg at 68 °F ; 0.13 mm Hg at 77° F (NTP, 1992);0.13 mmHg;0.13 mm Hg at 25 °C /Extrapolated/;Vapor pressure, Pa at 20 °C: 10.6;0.08 mmHg
• Viscosity: 0.581 cP at 20 °C
• XLogP3: -0.9

Custom Q&A

What are some of the uses of Propylene Glycol in the cosmetic and beauty industry?

Propylene Glycol is used as a humectant, skin conditioner, carrier in fragrance oils, solvents, and viscosity reducers in cosmetics.

What is the role of Propylene Glycol in moisturizers?

Propylene Glycol helps retain moisture in the skin by acting as a humectant, reducing flaking and restoring suppleness.

How does Propylene Glycol benefit the skin?

Propylene Glycol helps in moisturizing the skin, reducing signs of aging, enhancing the effect of other cosmetics ingredients, preventing water loss, and improving the condition of acne-prone skin.

What are some potential uses of Propylene Glycol outside of cosmetics?

Propylene Glycol is also used in food items, such as beer, baked goods, frozen dairy products, and butter, as well as in drugs as a solvent.

What are some benefits of Propylene Glycol for hair?

Propylene Glycol hair products help soften the hair, detangle it, prevent dryness and damage by retaining moisture, and make the hair frizz-free.

How is Propylene Glycol derived?

Propylene Glycol can be derived from natural gas, petroleum, or vegetable sources. When obtained from vegetable sources, glycerin and hydrogen are reacted together at high pressures and temperatures.

What are the functions of Propylene Glycol in a cosmetic formulation?

Propylene Glycol acts as an emollient, humectant, preservative, solvent, and viscosity controller in cosmetic formulations.

Is Propylene Glycol safe to use in cosmetic products?

Propylene Glycol is generally recognized as safe to use in cosmetic products. However, a patch test should be done prior to usage and any irritation or rashes should be reported to a dermatologist.

What precautions should be taken when using Propylene Glycol in cosmetics?

Propylene Glycol should not come into contact with damaged or burned skin, or with the eyes, mouth, and nose. A small amount should be tested on the arm before regular use, and it should be used with caution by individuals with eczema.

What are some characteristics of Propylene Glycol?

Propylene Glycol is a colorless, odorless liquid that is soluble in water. It is used in various formulations such as creams, lotions, serums, and shampoos in the cosmetic industry.