Catalog Number
ACM1272755562
Product Name
Fmoc-D-His(Clt)-OH
Description
Building block for introduction of D-histidine by Fmoc SPPS. The Clt group is more stable to acid than Trt and its use avoids the formation of partially protected histidine peptides during the preparation of protected fragments.
Synonyms
Fmoc-D-His(Clt)-OH, N-α-Fmoc-N-im-2-chlorotrityl-D-histidine
IUPAC Name
(2R)-3-[1-[(2-chlorophenyl)-diphenylmethyl]imidazol-4-yl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Molecular Formula
C40H32ClN3O4
Canonical SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=C(N=C4)CC(C(=O)O)NC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57
InChI
1S/C40H32ClN3O4/c41-36-22-12-11-21-35(36)40(27-13-3-1-4-14-27,28-15-5-2-6-16-28)44-24-29(42-26-44)23-37(38(45)46)43-39(47)48-25-34-32-19-9-7-17-30(32)31-18-8-10-20-33(31)34/h1-22,24,26,34,37H,23,25H2,(H,43,47)(H,45,46)/t37-/m1/s1
InChI Key
SYGADBVEKBWUKO-DIPNUNPCSA-N
Application
Peptide synthesis.
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
15-25℃
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