Fmoc-Asp-OtBu

• Catalog Number: ACM129460099
• Product Name: Fmoc-Asp-OtBu
• CAS: 129460-09-9
• Category: Amino Acids
• Description: Selectively protected building block for library synthesis or the preparation of β-aspartyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the β-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters and amides, and lactams and lactones containing the aspartyl unit.
• Synonyms: Fmoc-Asp-OtBu, N-α-Fmoc-L-aspartic acid α-t.-butyl ester
• Molecular Weight: 411.45
• Molecular Formula: C23H25NO6
• InChI: 1S/C23H25NO6/c1-23(2,3)30-21(27)19(12-20(25)26)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,26)/t19-/m0/s1
• InChI Key: VZXQYACYLGRQJU-IBGZPJMESA-N
• Melting Point: 90-98℃
• Application: Peptide synthesis.
• Assay: ≥90.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Form: powder
• Functional Group: carboxylic acid
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unlabeled Standard Amino Acids, Aspartic Acid (Asp)