Fmoc-Asp(OtBu)-(Dmb)Gly-OH

• Catalog Number: ACM900152729
• Product Name: Fmoc-Asp(OtBu)-(Dmb)Gly-OH
• CAS: 900152-72-9
• Category: Amino Acids
• Description: Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction. This derivative also completely inhibits aspartimide formation.
• Synonyms: Fmoc-Asp(OtBu)-(Dmb)Gly-OH, N-α-Fmoc-β-O-t.-butyl-L-aspartyl-N-α-(2,4-dimethoxybenzyl)-glycine
• Molecular Weight: 618.67
• InChI: 1S/C34H38N2O9/c1-34(2,3)45-31(39)19-36(18-21-14-15-22(42-4)16-29(21)43-5)32(40)28(17-30(37)38)35-33(41)44-20-27-25-12-8-6-10-23(25)24-11-7-9-13-26(24)27/h6-16,27-28H,17-20H2,1-5H3,(H,35,41)(H,37,38)/t28-/m0/s1
• InChI Key: JWWOZAAYQXZHGO-NDEPHWFRSA-N
• Application: Peptide synthesis.
• Assay: ≥90.0% (acidimetric); ≥97.0% (HPLC); ≥98% (TLC)
• Form: powder
• Functional Group: Fmoc
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-8℃