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Phenanthrenequinone | CAS Number: 84-11-7

Catalog Number
ACM84117
Product Name
Phenanthrenequinone
Structure
CAS Number
84-11-7
Synonyms
9,10-dihydro-9,10-dioxo-phenanthren;9,10-phenanthraquinone[qr];9,10-phenanthrenequinone[qr];phenanthraquinone[qr];Phenanthrene, 9,10-dihydro-9,10-dioxo-;phenanthrene,9,10-dihydro-9,10-dioxo-[qr];phenanthrenequinone[qr];Phenanthroquinone
Molecular Weight
208.21
Molecular Formula
C14H8O2
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1Chemical toxicology of reactive species in the atmosphere: two decades of progress in an electron acceptor and an electrophile.

Kumagai Y1, Abiko Y, Cong NL.

J Toxicol Sci. 2016;41(Special):SP37-SP47. doi: 10.2131/jts.41.SP37.

Air pollutants such as diesel exhaust particles (DEP) are thought to cause pulmonary diseases such as asthma as a result of oxidative stress. While DEP contain a large number of polycyclic aromatic hydrocarbons, we have focused on 9,10-phenanthrenequinone (9,10-PQ) and 1,2-naphthoquinone (1,2-NQ) because of their chemical properties based on their oxidative and chemical modification capabilities. We have found that 9,10-PQ interacts with electron donors such as NADPH (in the presence of enzymes) and dithiols, resulting in generation of excess reactive oxygen species (ROS) through redox cycling. Read More

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Contact us

Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA