Catalog Number
ACM47326863
Description
WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine (HY-18062)-resistant P. falciparum strains) as well as T. gondii.
Synonyms
1,6-Dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine;
IUPAC Name
6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine
Molecular Formula
C14H18Cl3N5O2
Canonical SMILES
CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C
InChI Key
MJZJYWCQPMNPRM-UHFFFAOYSA-N
Storage
Powder-20°C, 3 years; 4°C, 2 years; *The compound is unstable in solutions, freshly prepared is recommended..
Shipping
Can be shipped at room temperature, where not in use may vary.
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