Vinorelbine

• Catalog Number: ACM71486221
• Product Name: Vinorelbine
• CAS: 71486-22-1
• Category: Heterocyclic Organic Compound
• Synonyms: 5-Noranhydrovinblastine
• Molecular Weight: 778.9
• Molecular Formula: C₄₅H₅₄N₄O₈
• InChI: InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1
• InChI Key: GBABOYUKABKIAF-IELIFDKJSA-N
• Complexity: 1690
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 8
• Exact Mass: 778.39416469
• Heavy Atom Count: 57
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 2
• Isomeric SMILES: CCC1=C[C@H]2C[C@@](C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC
• Monoisotopic Mass: 778.39416469
• Physical State: Powder
• Rotatable Bond Count: 10
• Topological Polar Surface Area: 134 Ų

Custom Q&A

What is the molecular formula of Vinorelbine?

The molecular formula of Vinorelbine is C45H54N4O8.

What are the synonyms of Vinorelbine?

The synonyms of Vinorelbine include vinorelbine, 71486-22-1, Vinorelbine base, Vinorelbina, Vinorelbinum, and more.

What is the molecular weight of Vinorelbine?

The molecular weight of Vinorelbine is 778.9 g/mol.

When was Vinorelbine created?

Vinorelbine was created on December 16, 2005.

When was Vinorelbine last modified?

Vinorelbine was last modified on December 30, 2023.

What is the role of Vinorelbine?

Vinorelbine has a role as an antineoplastic agent and a photosensitizing agent.

What type of chemotherapy drug is Vinorelbine?

Vinorelbine is an anti-mitotic chemotherapy drug.

Which types of malignancies is Vinorelbine used to treat?

Vinorelbine is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC).

When was Vinorelbine initially approved in the USA?

Vinorelbine was initially approved in the USA in the 1990s for the treatment of NSCLC.

What did a study on Vinorelbine clearance rate reveal?

A study on the clearance rate of Vinorelbine showed a 4.3-fold variation in clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug.