Verteporfin

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Catalog Number
ACM129497785-1
Product Name
Verteporfin
Structure
Structure
CAS
129497-78-5
Category
Inhibitors
Description
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation.
Synonyms
Verteprofin; Verteporphin; trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester; Visudyne; VERTEPORFIN (200 MG);
IUPAC Name
Verteporfin
Molecular Weight
1437.61
Molecular Formula
C41H42N4O8
Canonical SMILES
C[C@]1(/C2=C/C(N3)=C4C)C(C(/C=C(C(C)=C/5C=C)\NC5=C/C6=N/C(C(CCC(OC)=O)=C6C)=C\C3=C4CCC(O)=O)=N2)=CC=C(C(OC)=O)[C@H]1C(OC)=O.C[C@]7(/C8=C/C(N9)=C%10C)C(C(/C=C(C(C)=C/%11C=C)\NC%11=C/C%12=N/C(C(CCC(O)=O)=C%12C)=C\C9=C%10CCC(OC)=O)=N8)=CC=C(C(OC)=O)[C@H]7C(OC)=O
Appearance
Powder
Storage
-20 °C
Exact Mass
1436.60000
Shipping
Can be shipped at room temperature, where not in use may vary.
Please kindly note that our products are for research use only.

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