Sodium copper chlorophyllin

• CAS: 28302-36-5
• Catalog Number: ACM28302365
• Category: Main Products
• Molecular Weight: 722.13
• Molecular Formula: C₃₄H₂₉CuN₄Na₃O₆
• Synonyms: SODIUM CHLOROPHYLLIN;SODIUM COPPER CHLOROPHYLLIN;[sp-4-2-(2s-trans)]-sodiu;7,17-trimethyl-21h,23h-porphine-2-propanoato(5-)-n21,n22,n23,n24]-hydro-tri;cuprate(3-),[18-carboxy-20-(carboxymethyl)-8-ethenyl-13-ethyl-12-formyl-2,3-di;CHLOROPHYLLIN WATER SOLUBLE;CHLOROPHYLLIN SODIUM-COPPER SALT;CHLOROPHYLLIN-COPPER COMPLEX FOOD DYE E 141
• IUPAC Name: copper,trisodium,3-[(2S,3S)-20-(carboxylatomethyl)-18-(dioxidomethylid...
• Boiling Point: 790ºC at 760mmHg
• Flash Point: 431.6ºC
• Appearance: dark green powder
• Exact Mass: 668.13300
• Safety Description: 22-24/25
• WGK Germany: 2

Case Study

Sodium Copper Chlorophyllin for Functionalization of Silver Nanoparticles in Photodynamic Applications

Habibi E, et al. Journal of Luminescence, 2024, 273, 120708.

Sodium copper chlorophyllin (SCC) is utilized as a photosensitizer for enhancing the photodynamic properties of nanoparticles (NPs). In this process, SCC is solubilized in deionized water, followed by the incorporation of ethyl dimethylamino carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to facilitate the covalent linkage between SCC and NPs. A solution containing the reagents is mixed with NPs to enable functionalization, creating a modified nanoparticle complex. This method, employing a 24-hour stirring period, results in the successful attachment of SCC to the surface of silver nanoparticles (Ag NPs). The resulting SCC-functionalized NPs can be applied in photodynamic therapy and other light-activated biomedical applications due to the efficient photosensitizing properties imparted by SCC.

Sodium Copper Chlorophyllin as an Effective Scavenger Against Aflatoxin B1-Induced Cytotoxicity via CYP3A4 Inhibition

Mishra M, et al. International Journal of Biological Macromolecules, 2024, 280(1), 135594.

Sodium copper chlorophyllin (SCC) exhibits significant pharmacological potential, particularly in mitigating the cytotoxic effects of aflatoxin B1 (AFB1), a potent carcinogen. The study focuses on the interaction between SCC and the Cytochrome P450 enzyme CYP3A4, which is implicated in drug metabolism but also plays a role in the activation of AFB1 to a cytotoxic epoxide. Computational studies reveal that SCC effectively binds to AFB1, blocking its carcinogenic effects by intercepting its interaction with CYP3A4. This results in a reduction in AFB1-induced cellular damage, highlighting SCC's potential as a therapeutic agent to combat AFB1-related cytotoxicity. The findings open avenues for further clinical research into SCC's role in pharmacology, offering promising prospects for its application in preventing or reducing the harmful effects of AFB1 exposure.

Sodium Copper Chlorophyllin in the Development of MAO/PMTMS-SCC Composite Coatings for Enhanced Mg Alloy Protection

Cui L-Y, et al. Corrosion Communications, 2025.

Sodium copper chlorophyllin (SCC) plays a crucial role in the development of composite coatings aimed at improving the surface properties of magnesium alloys. The SCC addition not only improved the mechanical properties of the coating but also endowed the composite with potential bioactive functions, highlighting its versatile application in materials science, particularly for corrosion protection in harsh environments. An MAO/PMTMS-SCC composite coating was prepared on AZ31 Mg alloy using a multi-step process. Initially, the magnesium alloy was anodized via micro-arc oxidation (MAO) in a phosphate and sodium hydroxide electrolyte to form a protective oxide layer. The surface was then treated with polymethyltrimethoxysilane (PMTMS) to enhance the coating's hydrophobic and corrosion-resistant properties.

Effect of Sodium Copper Chlorophyllin on Poly-Triarylamines Films for Enhanced Perovskite Solar Cells

Tian H, et al. Nano Energy, 2024, 126, 109616.

Sodium copper chlorophyllin (SCC) is used to modify poly-triarylamines (PTAA) films for perovskite solar cells. SCC is dissolved in ethanol and spin-coated onto the PTAA layer before perovskite deposition. X-ray photoelectron spectroscopy (XPS) confirms the successful coverage of SCC on the PTAA, indicated by the Cu 2p peak at 934.3 eV, absent in bare PTAA films. The wettability of the PTAA/SCC film is significantly enhanced, with a contact angle reduction from 91.3° to 23.4° as SCC concentration increases, improving the film's hydrophilicity. This modification aids in the better interaction between the PTAA and the perovskite precursor, leading to high-quality perovskite films. Ultraviolet photoelectron spectroscopy (UPS) reveals that SCC introduces a more favorable hole-transport layer (HTL) energy alignment, with HOMO and LUMO levels of -4.87 eV and -1.67 eV, respectively. This adjustment facilitates hole transfer from the perovskite layer to the HTL while blocking electron transfer, thus minimizing charge recombination at the interface. These properties of SCC enhance the performance and stability of perovskite solar cells.