D-Pantethine
D-Pantethine is an organic compound formed by two D-pantothenic acid molecules linked by a disulfide bond. It is commonly used as a dietary supplement or research reagent, and appears as a colorless to pale yellow viscous liquid or powder.
- Definition
- Features
- Applications
- Qualifications
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What is D-Pantethine?
D-Pantethine is a dimer form of pantothenic acid and a key intermediate in the biosynthesis of coenzyme A. It is widely used to improve blood cholesterol levels, as an adjunct treatment for acne, and as a lipid-lowering agent in scientific research.
What are the Features of D-Pantethine?
A Key Precursor to Coenzyme A
D-Pantethine is a dimer form of pantothenic acid (vitamin B5), which is converted into coenzyme A in the body. It participates in over 70 metabolic pathways, including fatty acid oxidation, carbohydrate metabolism, and amino acid breakdown, and is crucial for cellular energy production and lipid metabolism.
Clinical Applications in Improving Blood Lipids
D-Pantethine is widely used as a dietary supplement or medicine to lower blood cholesterol and triglyceride levels, improve abnormal lipid metabolism, and has potential anti-atherosclerotic properties.
Unstable Physicochemical Properties
D-Pantethine is typically a colorless to pale yellow viscous liquid, hygroscopic, and relatively unstable. It must be stored in a sealed container at low temperatures (2-8°C) to prevent decomposition.
What are the Applications of D-Pantethine?
Cardiovascular Health and Lipid Regulation
D-Pantethine is widely used as a lipid-lowering drug, reducing plasma total cholesterol, triglycerides, LDL cholesterol, and VLDL cholesterol.
Skin Health and Acne Treatment
As a dietary supplement, D-pantethine can be used to improve acne symptoms.
Liver Protection and Metabolic Support
D-Pantethine reduces oxidative damage to the liver and enhances liver enzyme function.
Research and Drug Development
D-Pantethine is used as a tool compound to explore the mechanisms of lipid metabolism, cell signaling pathways, and viral infection.
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